Abstract

DO.02.03

Decontamination characteristics of ocular Hydrofluoric acid burn with water, calciumgluconate 2% and Anti-HF by OCT examination

Schrage N. F.¹, Foerst M.², Frentz M.³, Spoeler F.^2
1Augenklinik Köln Merheim; ²Institut für Halbleitertechnik an der RWTH Aachen; ³Universitäts-Augenklinik RWTH Aachen

Objective: Ocular burns are via high resolution OCT technique now real time follow up events. Therefore we evaluated HF burns treated and untreated to learn on the efficacy of decontamination fluids usually recommended for HF burns.
Methods: Ex vivo eyes of slaughtered rabbits were exposed to 25 ul of 1,25 mol HF filter paper. After removing the filter no rinsing or immediate rinsing with water, calcium gluconate 2% or Anti HF solution from Prevor started for 15 min., continuous OCT observation was done during 75 min
Results: There was total penetration of the untreated corneas within 15 min, water rinsing resulted in deep stromal changes with less severity, calcium gluconate showed initial stop of burn but later progression Anti HF solution proofed to stop burn without any progression after 75 min. There was corneal opacity for water, calcium gluconate and no treatment, only Anti HF corneas remained clear.
Conclusions: There is significant difference in decontamination of HF from ocular tissue dependent on the type of rinsing fluid. Rinsing with water is better than no treatment, significant improvement is done by caclium gluconate rinsing but best results were found with Anti HF solution. The mechanism of decontamination is now directly accessible via OCT and comparisons of rinsing fluids are possible.

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