Abstract

DO.07.05

Update on the medical therapy of XFG

Konstas A. G. P.
1^st University Department of Ophthalmology, AHEPA Hospital, Thessaloniki/GR

Approximately 30% of PEX cases convert to PEXG during a 10 year period. Is 24-hour IOP fluctuation important in the development of optic nerve head damage in PEXG? When should we initiate IOP lowering therapy? Once medical therapy is needed in PEXG, the choice and efficacy of initial and stepwise therapy are of paramount importance. Since PEXG is different from POAG, optimal medical therapy may also differ in PEXG. What do we know of the 24-hour IOP efficacy of available medications in PEXG? What is the role of fixed combinations in the management of PEXG? In PEXG surgery is often required to decrease IOP within the target range and to reduce 24-hour IOP fluctuation. What is the best choice of surgery? Is trabeculectomy the only evidence-based type of filtering surgery in PEXG and how do other approaches such as non-penetrating filtering surgery fit in? These clinically important issues will be critically reviewed in this presentation.

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